Insulin resistance is one of the symptoms of metabolic syndrome and an early stage in developing type 2 diabetes. Your doctor will interpret your HOMA-IR in conjunction with your signs and symptoms, medical history, and other test results. The higher the number, the more resistant you are to insulin. If your HOMA-IR is high, your body is using more insulin than normal to keep your blood sugar in balance. Levels above 1.9 signal early insulin resistance, while levels above 2.9 signal significant insulin resistance. Generally, you have optimal insulin sensitivity if your HOMA-IR is less than 1. But they all agree that the higher your HOMA-IR gets, the more insulin resistant you are. Normal Rangeĭifferent studies provide slightly different ranges for HOMA-IR. Measuring insulin resistance directly is impractical, complicated, and doctors rarely use it (the method is called hyperinsulinemic-euglycemic glucose clamp).
Other recently-developed indirect measures of insulin resistance include HOMA2, QUICKI, and the triglyceride/ HDL ratio. While it might not be the best model overall, it’s still the most widely used model in clinical research. HOMA-IR was developed in the 80s and is an indirect measure: it is calculated from your fasting glucose and fasting insulin levels. HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) tells you and your doctor how much insulin your pancreas needs to make to control your blood sugar levels. Muscles take up 60-70%, the liver about 30%, and fat tissue around 10% of sugar from the blood. Insulin lowers blood sugar by increasing its uptake and storage in tissues. Insulin is the hormone pancreas releases after you eat and it signals an abundance of energy in the body. This condition is called “ insulin resistance”. When cells no longer respond to insulin, your body needs to release more insulin to control blood sugar levels. Your blood sugar ( glucose) levels may be normal, but if your insulin levels are high, your body is likely struggling to maintain blood sugar levels in balance.
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Read on to learn about what causes high HOMA-IR and how to improve insulin resistance with lifestyle and dietary modifications. This test was designed to measure insulin resistance, an early stage of type 2 diabetes that increases your risk of many chronic diseases. HOMA-IR tells you how much insulin your body needs to keep your blood sugar levels in check.
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